发明名称 |
METHOD FOR DELIVERING A PHARMACEUTICAL COMPOSITION TO PATIENT IN NEED THEREOF |
摘要 |
The present disclosure is directed to the use of naproxen, or pharmaceutically acceptable salt thereof, and esomeprazole, or pharmaceutically acceptable salt thereof in the manufacture of a pharmaceutical composition in unit dose form, wherein said esomeprazole, or pharmaceutically acceptable salt thereof, is released from said unit dose form at a specified pH, wherein one unit dose form is for administration as an AM dose and a second unit dose form is for administration about 10 hours later as a PM dose to target a specified pharmacokinetic profile. |
申请公布号 |
WO2010029335(A1) |
申请公布日期 |
2010.03.18 |
申请号 |
WO2009GB51108 |
申请日期 |
2009.09.03 |
申请人 |
ASTRAZENECA UK LIMITED;POZEN INC.;AULT, BRIAN;ORLEMANS, EVERARDUS;PLACHETKA, JOHN R.;SOSTEK, MARK |
发明人 |
AULT, BRIAN;ORLEMANS, EVERARDUS;PLACHETKA, JOHN R.;SOSTEK, MARK |
分类号 |
A61K9/20;A61K31/192;A61K31/4439;A61P1/04;A61P19/02 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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