| 发明名称 |
NEW BENZIMIDAZOLE DERIVATIVES |
| 摘要 |
The invention is concerned with novel benzimidazole derivatives of Formula (I) wherein A, n and R1 to R7 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds act on Farnesyl X receptor (FXR) and against cholesterol and lipid illnesses, diabetes, obesity, psoriasis, cancer, osteoporosis, Parkinson's and Alzheimer's disease.
|
| 申请公布号 |
CA2734034(A1) |
申请公布日期 |
2010.03.18 |
| 申请号 |
CA20092734034 |
申请日期 |
2009.09.01 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BENSON, GREGORY MARTIN;BLEICHER, KONRAD;FENG, SONG;GRETHER, UWE;KUHN, BERND;MARTIN, RAINER E.;PLANCHER, JEAN-MARC;RICHTER, HANS;TAYLOR, SVEN |
| 分类号 |
C07D235/18;A61K31/31;A61K31/41;A61K31/4184;A61K31/437;A61K31/4439;A61K31/444;A61P3/00;A61P19/00;A61P21/00;C07D401/04;C07D401/12;C07D401/14;C07D403/12;C07D495/04 |
主分类号 |
C07D235/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
