发明名称 |
LOCAL DELIVERY OF WATER-SOLUBLE OR WATER-INSOLUBLE THERAPEUTIC AGENTS TO THE SURFACE OF BODY LUMENS |
摘要 |
A method and device for local delivery of water-soluble or water-insoluble therapeutic agents to the surface of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with an amphiphilic polymer coating comprising a therapeutic agent and an amphiphilic polymer or co-polymer. The medical disposable device is inserted into a body lumen, and expanded to contact the amphiphilic polymer coating against the body lumen. The total solubility of the polymer or co-polymer in vivo prevents any embolic hazard associated with the amphiphilic polymer coating.
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申请公布号 |
US2010068170(A1) |
申请公布日期 |
2010.03.18 |
申请号 |
US20090558420 |
申请日期 |
2009.09.11 |
申请人 |
MICHAL EUGENE T;LERNER DANIEL J;POLLMAN MATTHEW J |
发明人 |
MICHAL EUGENE T.;LERNER DANIEL J.;POLLMAN MATTHEW J. |
分类号 |
A61K47/48;A61F2/958;A61K31/337;A61K31/573;A61K33/24;A61P9/10;A61P35/00;B05D3/00 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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