发明名称 |
MOLECULAR TARGETS AND METHODS TO IDENTIFY COMPOUNDS FOR TREATING BONE AND JOINT DEGENERATIVE DISEASES |
摘要 |
<p>The present invention relates to methods for identifying agents capable of inhibiting the expression or activity of proteins involved in the processes modulating osteoclastogenesis, which inhibition is useful in the prevention and / or treatment of bone and joint degenerative diseases and diseases involving aberrant activity or differentiation of osteoclasts. In particular, the present invention provides methods for identifying agents for use in the prevention and / or treatment of rheumatoid arthritis.</p> |
申请公布号 |
EP2162747(A2) |
申请公布日期 |
2010.03.17 |
申请号 |
EP20080774155 |
申请日期 |
2008.06.19 |
申请人 |
GALAPAGOS N.V. |
发明人 |
BRYS, REGINALD CHRISTOPHE XAVIER;VANDEGHINSTE, NICKERNEST RENE |
分类号 |
G01N33/68;C12N15/11 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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