| 摘要 |
<p>This invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, and R6 are described in this application. These compounds inhibit the enzymes MEK 1 and MEK 2, protein kinases that are components of the MAP kinase signal transduction pathway. As such the compounds have anti-hyperproliferative cellular activity and are thus useful in the treatment of cell proliferative disorders, such as cancer.</p> |
