发明名称 |
VERFAHREN ZUR BEHANDLUNG VON ERKRANKUNGEN MIT MANGEL AN THIOLHALTIGER VERBINDUNG |
摘要 |
Methods for therapy of cystic fibrosis and other conditions are provided. The methods comprise one or more agents capable of increasing thiol-containing compound transport via a transporter system (i.e. ABC transporters such as MDR-1 or MRP-2) in cells. Other embodiments include the use of agents to modulate transport of thiol-containing compounds within the cell. Therapeutic methods involve the administration of such agents to a patient afflicted with cystic fibrosis and/or another condition responsive to stimulation of thiol-containing compound transport. |
申请公布号 |
AT459355(T) |
申请公布日期 |
2010.03.15 |
申请号 |
AT20030781632T |
申请日期 |
2003.10.30 |
申请人 |
NATIONAL JEWISH HEALTH |
发明人 |
DAY, BRIAN;VELSOR, LEONARD |
分类号 |
A61K31/4402;A61K31/35;A61K31/353;A61K31/37;A61K31/428;A61K31/47;A61K31/60;A61K31/635;A61P11/00 |
主分类号 |
A61K31/4402 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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