发明名称 NOVEL METHOD FOR THE SYNTHESIS OF ANTICANCER (POLY)AMINOALKYLAMIN OACETAMIDE DERIVATIVES OF EPIPODOPHYLLOTOXIN.
摘要 <p>The invention relates to a novel method for preparing (poly)aminoalkylaminoacetamide compounds of epipodophyllotoxin, which can be used in therapeutics as anticancer agents. The invention includes a step comprising the condensation of a primary amine reactant, the amine functions of which are not protected, with 4β-chloroacetamido-4'-epipodophyllotoxin in an aprotic polar organic solvent.</p>
申请公布号 MX2010001556(A) 申请公布日期 2010.03.15
申请号 MX20100001556 申请日期 2008.09.23
申请人 PIERRE FABRE MEDICAMENT. 发明人 THIERRY IMBERT;YVES GUMINSKI;MARTIAL GROUSSEAUD
分类号 C07D493/04 主分类号 C07D493/04
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