发明名称 |
VERFAHREN ZUR HERSTELLUNG VON 7-AMINO-SYN-3,5- DIHYDROXYHEPTANSÄUREDERIVATEN UND ZWISCHENVERBINDUNGEN DIESESVERFAHRENS UND DEREN HERESTELLUNG |
摘要 |
<p>The invention relates to novel synthesis methods for the preparation of the intermediates, which are suitable for the preparation of statin derivatives, especially to novel synthesis methods of the intermediate of formula VI wherein R<SUB>a</SUB>' and R<SUB>c</SUB>' are each independently of the other hydrogen or a hydroxy-protecting group or together are a bridging hydroxy-protecting group, and R<SUB>b </SUB>is a carboxy-protecting group, which methods are carried out by conversion of the intermediate of formula XVI wherein R<SUB>a</SUB>' and R<SUB>c</SUB>' are each independently of the other hydrogen or a hydroxy-protecting group, R* and R** are each independently of the other hydrogen or an amide-protecting group, and R<SUB>b </SUB>is a carboxy-protecting group; which methods proceed to further new intermediates and methods for their preparation</p> |
申请公布号 |
AT457972(T) |
申请公布日期 |
2010.03.15 |
申请号 |
AT20020764615T |
申请日期 |
2002.07.02 |
申请人 |
BASF SE |
发明人 |
OEHRLEIN, REINHOLD;BAISCH, GABRIELE;KIRNER, HANS;BIENEWALD, FRANK;BURKHARDT, STEPHAN;STUDER, MARTIN |
分类号 |
C07C67/307;C07C227/32;C07B53/00;C07B61/00;C07C67/31;C07C69/67;C07C69/675;C07C69/708;C07C69/716;C07C69/732;C07C69/738;C07C227/06;C07C227/16;C07C229/22;C07C231/02;C07C235/04;C07C235/06;C07C235/74;C07C247/12;C07D207/34;C12P7/62 |
主分类号 |
C07C67/307 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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