发明名称 |
Kunstig dermis og fremstillingsfremgangsmåde dertil |
摘要 |
<p>Artificial dermis (1) obtained from plasma with platelets (2) and human fibroblasts. The plasma with platelets (2) is obtained from the fractionating of total blood (4) from the patient (8) by light centrifugation, and the human fibroblasts (3) from a skin biopsy (5). Clotting is obtained by adding calcium. <??>This artificial dermis (1) provides for the rapid growth of the keratinocytes (6) seeded on its surface to build an artificial skin (7) which can easily be transplanted. Large areas of artificial dermis (1) are obtained from a small skin biopsy (5) and minimal quantities of plasma with platelets (2), which being enriched with cytokines and platelet growth factors, strengthens the proliferation of the cells seeded, both inside and on the surface. <??>The artificial skin (7) obtained can be used to treat major burn treatments, chronic skin ulcers, etc., or be used, by employing genetically altered cells, as a vehicle for gene therapy. <IMAGE></p> |
申请公布号 |
DK1375647(T3) |
申请公布日期 |
2010.03.15 |
申请号 |
DK20020702424T |
申请日期 |
2002.02.28 |
申请人 |
CENTRO DE INVESTIGACIONES ENERGETICAS MEDIOAMBIENTALES Y TECNOLOGICAS (C.I.E.M.A.T.);CENTRO COMUNITARIO DE TRANSFUSION DE ASTURIAS-CRUZ ROJA ESPANOLA;FUNDACION MARCELINO BOTIN |
发明人 |
MEANA INFIESTA, ALVARO;GOMEZ LLANES, SARA;JORCANO NOVAL, JOSE LUIS;LARCHER LAGUZZI, FERNANDO;DEL RIO NECHAEVSKY, MARCELA |
分类号 |
A61L27/00;A61F2/10;A61L27/60;C12N5/08 |
主分类号 |
A61L27/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|