The present invention provides a pharmaceutical formulation comprising an immediate-release compartment containing hydrochlorothiazide as a pharmacologically active ingredient and an extended-release compartment containing losartan as a pharmacologically active ingredient. Since the formulation of the present invention can deliver hydrochlorothiazide and losartan at a specific rate at different times, it is very effective in treating hypertension and preventing complications, and has the effects of improving the adaptation rate of the patient, optimizing drug delivery time and reducing side effects.
申请公布号
WO2009134056(A9)
申请公布日期
2010.03.11
申请号
WO2009KR02224
申请日期
2009.04.28
申请人
HANALL PHARMACEUTICAL CO., LTD.;KIM, SUNG WUK;JUN, SUNG SOO;JO, YOUNG GWAN;KOO, JA SEONG;LEE, AH RAM;SON, JAE WOON;PARK, YUN SANG
发明人
KIM, SUNG WUK;JUN, SUNG SOO;JO, YOUNG GWAN;KOO, JA SEONG;LEE, AH RAM;SON, JAE WOON;PARK, YUN SANG