| 发明名称 |
Substituted isoquinoline and isoquinolinone derivatives as inhibitors of RHO-Kinase |
| 摘要 |
The invention relates to 6-substituted isoquinoline and isochinolone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
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| 申请公布号 |
US2010063025(A1) |
申请公布日期 |
2010.03.11 |
| 申请号 |
US20090487403 |
申请日期 |
2009.06.18 |
| 申请人 |
SANOFI-AVENTIS |
发明人 |
PLETTENBURG OLIVER;HOFMEISTER ARMIN;BRENDEL JOACHIM;LOEHN MATTHIAS |
| 分类号 |
A61K31/4725;A61K31/55;A61P1/16;A61P3/00;A61P3/10;A61P9/00;A61P9/10;A61P9/12;A61P11/00;A61P25/00;A61P35/00;C07D401/12;C07D401/14 |
主分类号 |
A61K31/4725 |
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