发明名称 LIGHT-STABLE SOLID PHARMACEUTICAL COMPOSITION OF RAMOSETRON
摘要 Provided is a preparation of ramosetron which is stable under irradiation with light. The solid pharmaceutical composition of the present invention can provide a stable preparation by blending a compound absorbing light having a specific wavelength with ramosetron which is unstable, usually under irradiation with light, or a pharmaceutically acceptable salt thereof. Particularly, this technique is useful because it is adaptable to a preparation containing ramosetron or a pharmaceutically acceptable salt thereof at a low content or an orally disintegrating tablet containing ramosetron or a pharmaceutically acceptable salt thereof. Also, the present invention relates to a method for stabilizing a solid pharmaceutical composition of ramosetron or a pharmaceutically acceptable salt thereof, which is characterized by blending a compound having characteristics of absorbing light having a specific wavelength.
申请公布号 US2010062063(A1) 申请公布日期 2010.03.11
申请号 US20070441006 申请日期 2007.09.12
申请人 ASTELLAS PHARMA INC. 发明人 UMEJIMA HIROYUKI;KURIMOTO IPPEI;KANBAYASHI ATSUSHI;MORI CHIEKO
分类号 A61K31/4184;A61K9/14;A61K9/28;A61P1/08 主分类号 A61K31/4184
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