CELL LINES EXPRESSING GABA RECEPTOR AND METHODS USING THEM

摘要

The invention relates to Gamma -aminobutyric acid receptors (GABA receptors) as well as cells and cell lines stably expressing a GABA receptor. The invention includes cell lines that express various subunit combinations of GABA receptors. The GABA receptor-expressing cell lines are highly sensitive, physiologically relevant and produce consistent results. The invention further provides methods of making such cells and cell lines. The GABA receptor-expressing cells and cell lines provided herein are useful in identifying modulators of GABA receptors.