MONOCLONAL ANTIBODY AND IMMUNOASSAY USING THE SAME

摘要

Disclosed are: an anti-human immunoglobulin M monoclonal antibody which can react with human immunoglobulin M specifically to form an immunological aggregate through the antigen-antibody reaction with the human immunoglobulin M in a solution; an immunoassay using the monoclonal antibody; an inhibitor which can inhibit a non-specific reaction induced by human immunoglobulin M which cannot be inhibited by the conventional techniques; and an immunoassay in which a non-specific reaction induced by human immunoglobulin M is inhibited. In the selection of a monoclonal antibody capable of reacting with human immunoglobulin M by employing the reactivity in a solution as a measure for the evaluation, it becomes possible to produce a novel monoclonal antibody which can cause the aggregation of human immunoglobulin M by itself and enables a practical immunoagglutination measurement.