发明名称 |
NEW PHENYLACETATE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, METHOD FOR PRODUCING THE SAME, AND PROPHYLACTIC OR THERAPEUTIC COMPOSITION FOR DISEASE INDUCED BY ACTIVITATION OF TYPE T CALCIUM ION CHANNEL CONTAINING THE SAME AS ACTIVE INGREDIENT |
摘要 |
PROBLEM TO BE SOLVED: To provide a phenylacetate derivative effectively inhibiting activation of type T calcium ion channels or a pharmaceutically acceptable salt thereof. SOLUTION: There are provided the new phenylacetate derivative represented by chemical formula or the pharmaceutically acceptable salt thereof; a method for producing the same; and a prophylactic or therapeutic composition for diseases induced by the activation of the type T calcium ion channels containing the same as an active ingredient. Since the composition containing the phenylacetate derivative effectively inhibits the activation of the type T calcium ion channels, the composition can be effectively used as a prophylactic or therapeutic agent for the diseases such as hypertension, cancer, epilepsy, or neurogenic pain induced by the activation of the type T calcium ion channels. COPYRIGHT: (C)2010,JPO&INPIT
|
申请公布号 |
JP2010053115(A) |
申请公布日期 |
2010.03.11 |
申请号 |
JP20080316342 |
申请日期 |
2008.12.12 |
申请人 |
KOREA INST OF SCIENCE & TECHNOLOGY |
发明人 |
SHIN KYE JUNG;LEE HYUNG KOOK;ROH EUN JOO;PAE AE NIM;SEO SEON HEE;BAEK YI YEON;KIM YOON JEE;SHIN HEE SUP;KIM DONG JIN;CHOI KYUNG IL;RHIM HYE WHON;CHUNG HYE JIN;NAM GHIL SOO;CHO YONG SEO;CHOO HYUN AH;HAHN HOH GYU;KANG SOON BANG;SHIN DONG YUN;CHEONG CHAN SEONG;KIM EUN KYEONG;CHUNG HE SSON;KIM KEY SUN;KEUM GYO CHANG;LEE CHEOL JU;SUN JUUN MIN;NAM KEE DAL;LEE JAE KYUN;KANG YONG KOO;PARK WOONG SEO;KIM YOUNG SOO;CHOI KEE HYUN;CHII MAN SON |
分类号 |
C07D211/14;A61K31/4184;A61K31/445;A61K31/495;A61P9/12;A61P25/02;A61P25/08;A61P35/00;A61P43/00;C07C69/614;C07C69/65;C07C69/734;C07D211/18;C07D211/22;C07D211/70;C07D235/14;C07D295/14 |
主分类号 |
C07D211/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|