发明名称 NEW PHENYLACETATE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, METHOD FOR PRODUCING THE SAME, AND PROPHYLACTIC OR THERAPEUTIC COMPOSITION FOR DISEASE INDUCED BY ACTIVITATION OF TYPE T CALCIUM ION CHANNEL CONTAINING THE SAME AS ACTIVE INGREDIENT
摘要 PROBLEM TO BE SOLVED: To provide a phenylacetate derivative effectively inhibiting activation of type T calcium ion channels or a pharmaceutically acceptable salt thereof. SOLUTION: There are provided the new phenylacetate derivative represented by chemical formula or the pharmaceutically acceptable salt thereof; a method for producing the same; and a prophylactic or therapeutic composition for diseases induced by the activation of the type T calcium ion channels containing the same as an active ingredient. Since the composition containing the phenylacetate derivative effectively inhibits the activation of the type T calcium ion channels, the composition can be effectively used as a prophylactic or therapeutic agent for the diseases such as hypertension, cancer, epilepsy, or neurogenic pain induced by the activation of the type T calcium ion channels. COPYRIGHT: (C)2010,JPO&INPIT
申请公布号 JP2010053115(A) 申请公布日期 2010.03.11
申请号 JP20080316342 申请日期 2008.12.12
申请人 KOREA INST OF SCIENCE & TECHNOLOGY 发明人 SHIN KYE JUNG;LEE HYUNG KOOK;ROH EUN JOO;PAE AE NIM;SEO SEON HEE;BAEK YI YEON;KIM YOON JEE;SHIN HEE SUP;KIM DONG JIN;CHOI KYUNG IL;RHIM HYE WHON;CHUNG HYE JIN;NAM GHIL SOO;CHO YONG SEO;CHOO HYUN AH;HAHN HOH GYU;KANG SOON BANG;SHIN DONG YUN;CHEONG CHAN SEONG;KIM EUN KYEONG;CHUNG HE SSON;KIM KEY SUN;KEUM GYO CHANG;LEE CHEOL JU;SUN JUUN MIN;NAM KEE DAL;LEE JAE KYUN;KANG YONG KOO;PARK WOONG SEO;KIM YOUNG SOO;CHOI KEE HYUN;CHII MAN SON
分类号 C07D211/14;A61K31/4184;A61K31/445;A61K31/495;A61P9/12;A61P25/02;A61P25/08;A61P35/00;A61P43/00;C07C69/614;C07C69/65;C07C69/734;C07D211/18;C07D211/22;C07D211/70;C07D235/14;C07D295/14 主分类号 C07D211/14
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