| 摘要 |
Described herein are methods, compositions and kits related to manipulating hematopoietic stem cells (HSC) and more particularly to methods, compositions and kits related to increasing the number of hematopoietic stem cells in vitro, ex vivo and/or in vivo. Also described are methods, compositions and kits related to making an expanded population of HSC and methods, compositions and kits related to using the expanded population of HSC. For example, HSC growth may be enhanced by contacting the nascent stem cells or HSC with an agent that stimulates the nitric oxide signaling pathway. |
| 申请人 |
CHILDREN'S MEDICAL CENTER CORPORATION;THE GENERAL HOSPITAL CORPORATION;BETH ISRAEL DEACONESS MEDICAL CENTER, INC.;THE BRIGHAM AND WOMEN'S HOSPITAL, INC.;ZON, LEONARD, I.;NORTH, TRISTA, E.;GOESSLING, WOLFRAM |
发明人 |
ZON, LEONARD, I.;NORTH, TRISTA, E.;GOESSLING, WOLFRAM |
