发明名称 SUBSTITUTED HYDANTOINS
摘要 FIELD: chemistry. ^ SUBSTANCE: described are compounds of formula (I) ^ Values of radicals R1-R6 are given in the formula of invention. The compounds inhibit protein kinase MEK1/2. Also described is a pharmaceutical composition for administration in diseases mediated by MEK1/2. ^ EFFECT: compounds are highly efficient. ^ 16 cl, 27 ex
申请公布号 RU2383542(C2) 申请公布日期 2010.03.10
申请号 RU20070109651 申请日期 2005.08.09
申请人 F.KHOFFMANN-LJA ROSH AG 发明人 CHU SIN'TSZI;FOTUI NADER;KH'JUBI NIKOLAS DZHON SILVESTER;KONG NORMAN;MAKDERMOTT LI APOSTLE;MOLITERNI DZHON ANTONI;DZHAN DZHUMIN
分类号 A61K31/427;A61P35/00;C07D417/12;C07D417/14 主分类号 A61K31/427
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