N-CARBAMOYLMETHYL-4(R)-PHENYL-2-PYRROLIDINONE, METHOD OF ITS PREPARATION AND PHARMACEUTICAL USE
摘要
<p>The invention relates to the R-enantiomer of N-carbamoylmethyl-4-phenyl-2-pyrrolidinone (R-Carphedon) of pharmacological value. The method of its preparation includes the N-alkylation of 4(R)-phenyl-2-pyrrolidinone with ethyl bromoacetate in the presence of a strong base and the treatment of intermediate N-ethoxycarbonylmethyl-4(R)-phenyl-2-pyrrolidinone with ammonia.</p>
申请公布号
EP2013166(B1)
申请公布日期
2010.03.10
申请号
EP20070726915
申请日期
2007.03.15
申请人
AKCIJU SABIEDRIBA "OLAINFARM"
发明人
VEINBERG, GRIGORY;VORONA, MAKSIM;ZVEJNIECE, LIGA;CHERNOBROVIJS, ALEKSANDRS;KALVINSH, IVARS;KARINA, LIGITA;DAMBROVA, MAIJA
