METHOD FOR SYNTHESIS OF 1,2,3,4,5,6,10,11,12,13,14,15,15a,15b-TETRADECAHYDRODICYCLONONE [b, d] SELENOPHENE

摘要

FIELD: chemistry. ^ SUBSTANCE: method for synthesis of 1,2,3,4,5,6,10,11,12,13,14,15,15a,15b-tetradecahydrodicyclonone[b,d]selenophene with general formula (1): ^ involves reacting cyclonone-1,2-diene with ethyl aluminium dichloride (EtAlCl2) in the presence of Mg (powder) and a zirconocene dichloride catalyst (Cp2ZrCl2), taken in molar ratio cyclonone-1,2-diene: EtAlCl2: Mg: Cp2ZrCl2-20:(11-13):20:(1.0-1.4), preferably 20:12:20:1.2. The reaction is carried out in an argon atmosphere at room temperature (20-22C) and atmospheric pressure for 6-8 hours in tetrahydrofuran, with subsequent addition of an amount of selenium (Se) which is equimolar to EtAlCl2, benzene as a solvent and heating the reaction mass for 7 hours at temperature of approximately 80C. ^ EFFECT: obtaining a compound with high selectivity. ^ 1 cl, 1 ex, 1 tbl