发明名称 |
A PROCESS FOR STEREOSELECTIVE SYNTHESIS OF LAMIVUDINE |
摘要 |
<p>The present invention discloses a process for stereoselective synthesis of Lamivudine comprising the following steps: (a) performing a glycosylation reaction between the compound of formula (I) and cytosine or protected cytosine, and separating the reaction product by recrystallization to obtain the intermediate of formula (II); and (b) deprotecting the intermediate of formula (II) to obtain Lamivudine.</p> |
申请公布号 |
EP2161267(A1) |
申请公布日期 |
2010.03.10 |
申请号 |
EP20070721605 |
申请日期 |
2007.06.29 |
申请人 |
SHANGHAI DESANO PHARMACEUTICAL HOLDING CO., LTD. |
发明人 |
LI, JINLIANG;LV, FENG |
分类号 |
C07D411/04;A61P31/18;A61P31/20;C07D327/04 |
主分类号 |
C07D411/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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