发明名称 |
POLYCYCLIC INDAZOLE DERIVATIVES AND THEIR USE AS ERK INHIBITORS FOR THE TREATMENT OF CANCER |
摘要 |
Disclosed are the ERK inhibitors of formula 1.0: (Chemical formula should be inserted here as it appears on abstract in paper form) and the pharmaceutically acceptable salts, esters and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a double bond in the ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
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申请公布号 |
KR20100025553(A) |
申请公布日期 |
2010.03.09 |
申请号 |
KR20097027487 |
申请日期 |
2008.06.04 |
申请人 |
SCHERING CORPORATION |
发明人 |
COOPER ALAN;DENG YONGQI;SHIPPS GERALD W. JR.;SHIH NENG YANG;ZHU HUGH;KELLY JOSEPH;DOLL RONALD;NAN YANG;DESAI JAGDISH;WANG JAMES;PALIWAL SUNIL;TSUI HON CHUNG;BOGA SOBHANA BABU;ALHASSAN ABDUL BASIT;GAO XIAOLEI;ZHU LIANG;PATEL MEHUL |
分类号 |
C07D403/14;A61K31/506;A61P35/00;C07D417/14 |
主分类号 |
C07D403/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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