| 发明名称 |
Treatment of cancer using HSV mutant |
| 摘要 |
Use as an anti-cancer agent of a mutant herpes simplex virus wherein the mutant virus comprises a modification in theγ34.5 gene in the long repeat region (RL) such that theγ34.5 gene is a non-functional, manufacture of medicaments and methods of testing cancer in mammals employing HSV mutant.
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| 申请公布号 |
US7674468(B2) |
申请公布日期 |
2010.03.09 |
| 申请号 |
US20050152591 |
申请日期 |
2005.06.13 |
| 申请人 |
CRUSADE LABORATORIES LIMITED;THE WISTAR INSTITUTE |
发明人 |
MACLEAN ALASDAIR RODERICK;BROWN SUSANNE MOIRA;FRASER NIGEL WILLIAM;RANDAZZO BRUCE PAUL |
| 分类号 |
A61K39/12;C12N15/09;A61K35/76;A61K39/245;A61P35/00;C12N7/00;C12N15/00;C12N15/38;C12R1/92 |
主分类号 |
A61K39/12 |
| 代理机构 |
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代理人 |
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