发明名称 |
Process for producing cyclic compounds |
摘要 |
The invention includes methods of processing an initial di-carbonyl compound by conversion to a cyclic compound. The cyclic compound is reacted with an alkylating agent to form a derivative having an alkylated ring nitrogen. The invention encompasses a method of producing an N-alkyl product. Ammonia content of a solution is adjusted to produce a ratio of ammonia to di-carboxylate compound of from about 1:1 to about 1.5:1. An alkylating agent is added and the initial compound is alkylated and cyclized. The invention includes methods of making N-methyl pyrrolidinone (NMP). Aqueous ammonia and succinate is introduced into a vessel and ammonia is adjusted to provide a ratio of ammonia to succinate of less than 2:1. A methylating agent is reacted with succinate at a temperature of from greater than 100° C. to about 400° C. to produce N-methyl succinimide which is purified and hydrogenated to form NMP.
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申请公布号 |
US7674916(B2) |
申请公布日期 |
2010.03.09 |
申请号 |
US20070688022 |
申请日期 |
2007.03.19 |
申请人 |
BATTELLE MEMORIAL INSTITUTE |
发明人 |
WERPY TODD A.;FREY, JR. JOHN G.;WHITE JAMES F.;HOLLADAY JOHNATHAN E.;ZACHER ALAN H. |
分类号 |
C07D207/267;C07D207/40;C07D207/404;C07D213/63 |
主分类号 |
C07D207/267 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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