发明名称 |
Stable oxaliplatin formulation |
摘要 |
A storage stable pharmaceutical composition comprising a solution of Oxaliplatin in water and a catalytic amount of a carbohydrate. A process for forming such pharmaceutical composition comprising dissolving a known amount of Oxaliplatin in water; adding an amount of carbohydrate in the range of 0.0010% to 0.05% w/v with respect to such solution; agitating the mixture to get clear solution; filtering it through a filter membrane under aseptic conditions; and filling the solution resulting into glass vials sealed with elastomeric stoppers and aluminium flip-off seals.
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申请公布号 |
US7674824(B2) |
申请公布日期 |
2010.03.09 |
申请号 |
US20060515553 |
申请日期 |
2006.09.05 |
申请人 |
FRESENIUS KABI ONCOLOGY LIMITED |
发明人 |
UPADHYAY SATISH CHANDRA;PANANCHUKUNNATH MANOJ KUMAR;SINGH AJEET KUMAR;JAIN DEEPTI;PARSHOTAMDAS DEEPAK JUDGELAL;MUKHARJEE RAMA;BURMAN ANAND C |
分类号 |
A61K31/282 |
主分类号 |
A61K31/282 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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