| 发明名称 |
C-21 modified epothilones, method for their preparation, pharmaceutical composition containing thereof and use |
| 摘要 |
<p>Described are epothilones having modified thiazole substituent of the general formula (I), where substituents have the meaning explained in description, a method for their preparation and pharmaceutical compositions containing thereof. The compounds are suited for the preparation of pharmaceutical compositions for treating cancer and other proliferative diseases, for inhibiting angiogenesis and for inducing apoptosis.</p> |
| 申请公布号 |
SK287200(B6) |
申请公布日期 |
2010.03.08 |
| 申请号 |
SK20010001078 |
申请日期 |
2000.02.17 |
| 申请人 |
GESELLSCHAFT FUER BIOTECHNOLOGISCHE FORSCHUNG MBH(GBF);BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
HOEFLE GERHARD;GLASER NICOLE;LEIBOLD THOMAS;VITE GREGORY;KIM SOONG-HOON |
| 分类号 |
A61K31/425;A61P35/00;C07D417/06;C07D493/04 |
主分类号 |
A61K31/425 |
| 代理机构 |
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