发明名称 |
CONTROLLED RELEASE DOSAGE FORMS OF ZOLPIDEM |
摘要 |
A controlled release dosage forms comprising zolpidem or a salt thereof to release zolpidem to induce rapid onset of sleep, and continue to release zolpidem in a controlled manner to maintain effective plasma concentrations over an extended period of time to improve sleep maintenance. The pharmaceutical controlled-release dosage form of zolpidem or a salt thereof having a dissolution profile when measured in a type I or II dissolution apparatus according to the U.S. Pharmacopoeia in 0.01M hydrochloric acid buffer at 37° C., such that less than 40% is released at the end of 30 minutes.
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申请公布号 |
US2010055181(A1) |
申请公布日期 |
2010.03.04 |
申请号 |
US20070517487 |
申请日期 |
2007.02.07 |
申请人 |
LUPIN LIMITED |
发明人 |
BHANDARI NILESH;RAGHAVAN VINEETH;JAYANTHI SURYA KUMAR;SEN HIMADRI |
分类号 |
A61K9/32;A61K9/10;A61K9/16;A61K9/20;A61K31/437 |
主分类号 |
A61K9/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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