发明名称 |
RADIOLABELED ANNEXINS |
摘要 |
A radiolabeled annexin comprising at least 2 up to 20 histidine residues at its N-terminus is disclosed. At least two of said histidine residues are adjacent or separated by no more than one other amino acid. The radiolabeled annexin is a stable complex with a radionuclide such as technetium 99m. The radiolabeled annexin can be used in a method of imaging cell death in a nucleated cell within a region of a mammalian subject in vivo. |
申请公布号 |
CA2735214(A1) |
申请公布日期 |
2010.03.04 |
申请号 |
CA20092735214 |
申请日期 |
2009.08.26 |
申请人 |
MOSAMEDIX B.V. |
发明人 |
REUTELINGSPERGER, CHRISTIAAN PETER MARIA;MOONEN, PETER JOZEF JACOBUS |
分类号 |
A61K51/08;C07K14/47;G01T1/161 |
主分类号 |
A61K51/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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