| 发明名称 |
INDOLEAMINE 2,3-DIOXYGENASE, PD-1/PD-L PATHWAYS, AND CTLA4 PATHWAYS IN THE ACTIVATION OF REGULATORY T CELLS |
| 摘要 |
The present invention includes methods of enhancing immune responses by administering an inhibitor of indoleamine-2,3-dioxygenase (IDO) along with one or more inhibitors of the PD-1/PD-L pathway and/or one or more inhibitors of the CTLA4 pathway.
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| 申请公布号 |
US2010055111(A1) |
申请公布日期 |
2010.03.04 |
| 申请号 |
US20080526909 |
申请日期 |
2008.02.14 |
| 申请人 |
MED. COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC.;REGENTS OF THE UNIVERSITY OF MINNESOTA |
发明人 |
SHARMA MADHAV D.;BLAZAR BRUCE R.;MELLOR ANDREW L.;MUNN DAVID H. |
| 分类号 |
A61K39/395;A61P31/00;A61P35/00;A61P37/04 |
主分类号 |
A61K39/395 |
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