发明名称 |
SYNGR4 FOR TARGET GENES OF CANCER THERAPY AND DIAGNOSIS |
摘要 |
<p>The present invention relates to the roles played by the SYNGR4 genes in lung cancer carcinogenesis and features a method for treating or preventing lung cancer by administering a double-stranded molecule against one or more of the SYNGR4 genes or a composition, vector or cell containing such a double stranded molecule and antibody. The present invention also features methods for diagnosing lung cancer or assessing/determining the prognosis of a patient with lung cancer, especially NSCLC or SCLC, using one or more over-expressed genes selected from among SYNGR4. To that end, SYNGR4 may serve as a novel serological biomarker for lung cancer. Also, disclosed are methods of identifying compounds for treating and preventing lung cancer, using as an index their effect on the over-expression of one or more of SYNGR4 in the lung cancer.</p> |
申请公布号 |
WO2010023866(A1) |
申请公布日期 |
2010.03.04 |
申请号 |
WO2009JP04059 |
申请日期 |
2009.08.24 |
申请人 |
ONCOTHERAPY SCIENCE, INC.;NAKAMURA, YUSUKE;DAIGO, YATARO;TOGASHI, AKIRA |
发明人 |
NAKAMURA, YUSUKE;DAIGO, YATARO;TOGASHI, AKIRA |
分类号 |
C12N15/09;A61K31/713;A61K48/00;A61P35/00;C12Q1/68;G01N33/15;G01N33/53 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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