| 发明名称 |
METHOD AND COMPOSITIONS FOR ENHANCED ANTI-TUMOR EFFECTOR FUNCTIONING OF T CELLS |
| 摘要 |
<p>Integration of costimulatory signaling domains within a tumor targeting chimeric antigen receptor (CAR), such as the IL13Ra2 specific IL13-zetakine (IL13?), enhances T cell-mediated responses against tumors even in the absence of expressed ligands for costimulatory receptors.</p> |
| 申请公布号 |
WO2010025177(A1) |
申请公布日期 |
2010.03.04 |
| 申请号 |
WO2009US55029 |
申请日期 |
2009.08.26 |
| 申请人 |
CITY OF HOPE;JENSEN, MICHAEL |
发明人 |
JENSEN, MICHAEL |
| 分类号 |
C07K14/435;A61K48/00;C07H21/00 |
主分类号 |
C07K14/435 |
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