发明名称 |
ADIPONECTIN FOR THE TREATMENT AND DIAGNOSIS OF ALBUMINURIA |
摘要 |
Disclosed are methods relating to the treatment and/or prevention of kidney disorders, especially kidney disorders characterized by or involving albuminuria. Methods described include the administration of an adiponectin polypeptide or a nucleic acid encoding such a polypeptide to treat or prevent the development of albuminuria. Also described are methods in which adiponectin is measured as a predictor of a subject's likelihood of having or developing a kidney disorder characterized by or involving albuminuria. Also described are methods of treating or preventing a kidney disorder involving administering an AMPK agonist and/or an inhibitor of Nox4 activity.
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申请公布号 |
US2010056445(A1) |
申请公布日期 |
2010.03.04 |
申请号 |
US20070446773 |
申请日期 |
2007.11.07 |
申请人 |
THOMAS JEFFERSON UNIVERSITY |
发明人 |
SHARMA KUMAR;GOLDSTEIN BARRY |
分类号 |
A61K38/17;A61K31/7088;C12Q1/68;G01N33/00;G01N33/53 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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