发明名称 |
MODIFIED RELEASE PHARMACEUTICAL COMPOSITION AND A PROCESS OF MAKING THE SAME |
摘要 |
The present invention refers to a modified release pharmaceutical composition comprising an in-situ gelling agent (=0.5 % w/w) and a gellation facilitating agent (e.g. calcium sulfate) in an amount of 2-17.5 % w/w. Additionally, the composition contains a release rate controlling polymer such as an acrylate and optionally a pH independent rate controlling polymer such as HPMC. A preferred active agent is mycophenolate mofetil. A process of making the above described composition is also disclosed.
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申请公布号 |
US2010056493(A1) |
申请公布日期 |
2010.03.04 |
申请号 |
US20080522185 |
申请日期 |
2008.01.24 |
申请人 |
JAIN RAJESH;JINDAL KOUR CHAND;BOLDHANE SANJAY |
发明人 |
JAIN RAJESH;JINDAL KOUR CHAND;BOLDHANE SANJAY |
分类号 |
A61K31/554;A61K31/5377 |
主分类号 |
A61K31/554 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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