发明名称 |
OXOTETRAHYDROFURAN-2-YL-BENZIMIDAZOLE DERIVATIVE |
摘要 |
The present invention relates to compounds, which are useful for treatment and/or prevention of diabetes mellitus, diabetes mellitus complications or obesity, since the compounds have glucokinase-activating effects, and are presented in Formula (I): wherein R1 represents a carbamoyl group; R2 represents a lower alkyl group; both of X1 and X2 represent CH, or any one of X1 and X2 represents a nitrogen atom and the other represents CH; a group of represents a group selected from the group consisting of a pyridinyl, a pyrazinyl, a pyrazolyl, a thiadiazolyl, a triazolyl, an isoxazolyl and a thiazolyl group; and k is zero or 1, or relates to pharmaceutically acceptable salts thereof.
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申请公布号 |
CA2734981(A1) |
申请公布日期 |
2010.03.04 |
申请号 |
CA20092734981 |
申请日期 |
2009.08.03 |
申请人 |
BANYU PHARMACEUTICAL CO., LTD. |
发明人 |
IINO, TOMOHARU;ASAI, MASANORI;OHNO, AKIO;INAMURA, SEIICHI;ISHIKAWA, MAKOTO;OHTAKE, NORIKAZU |
分类号 |
C07D405/14;A61K31/4439;A61K31/444;A61K45/00;A61P3/04;A61P3/10;A61P9/10;A61P13/12;A61P25/02;A61P27/02;A61P43/00 |
主分类号 |
C07D405/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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