发明名称 |
CYTOTOXIC T CELL DEFINED EGFR PEPTIDE AND AN OPTIMIZED DERIVATIVE PEPTIDE |
摘要 |
The invention provides a polypeptide having a sequence of amino acids consisting of IXDFGLAKL (SEQ ID NO: 1), as well as a nucleic acid encoding the polypeptide, vector comprising the nucleic acid, cell comprising the vector, and compositions thereof. The invention also provides a method of inducing a T-cell response in a patient with epithelial cancer, and a method inhibiting epithelial cancer, wherein the methods comprise administering the composition of the invention. |
申请公布号 |
WO2009149094(A3) |
申请公布日期 |
2010.03.04 |
申请号 |
WO2009US45986 |
申请日期 |
2009.06.02 |
申请人 |
UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION;FERRIS, ROBERT, L.;ANDRADE, PEDRO;LOPEZ-ALBAITERO, ANDRES |
发明人 |
FERRIS, ROBERT, L.;ANDRADE, PEDRO;LOPEZ-ALBAITERO, ANDRES |
分类号 |
C07K7/06;A61K38/08;A61P35/00;C12N15/11;C12N15/63 |
主分类号 |
C07K7/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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