发明名称 |
POTENTIATOR OF ACTIVITY OF ANTI-CANCER AGENT AND USE THEREOF, AND BIOMARKER FOR PREDICTION OF PROGNOSIS IN CANCER PATIENT AND USE THEREOF |
摘要 |
<p>Disclosed is a means for improving the clinical outcomes of cancer therapy. Specifically disclosed is an activity potentiator comprising a compound capable of inhibiting the expression of RFP (RET finger protein) gene or the activity of RFP as an active ingredient. The activity of an anti-cancer agent having an oxidative stress inducing ability can be potentiated by using the anti-cancer agent in combination with the activity potentiator. Further specifically disclosed are a biomarker useful for the recognition of prognosis in a cancer patient and use of the biomarker.</p> |
申请公布号 |
WO2010023917(A1) |
申请公布日期 |
2010.03.04 |
申请号 |
WO2009JP04162 |
申请日期 |
2009.08.27 |
申请人 |
NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY;TAKAHASHI, MASAHIDE;KATO, TAKUYA;KIKKAWA, FUMITAKA |
发明人 |
TAKAHASHI, MASAHIDE;KATO, TAKUYA;KIKKAWA, FUMITAKA |
分类号 |
A61K45/00;A61K31/7105;A61K31/711;A61K31/713;A61K38/43;A61K45/06;A61K48/00;A61P35/00;A61P35/02;A61P43/00;C12N15/09;C12Q1/68;G01N33/48;G01N33/53 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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