| 发明名称 |
PURIFIED RHIGF-I/RHIGFBP-3 COMPLEXES AND THEIR METHOD OF MANUFACTURE |
| 摘要 |
Complexes of IGF-I and IGFBP-3 with new levels of purity are provided. Chromatographic techniques have been developed that remove contaminants, such as mass and charge variants of IGFBP-3. The new techniques enable the production of high-quality pharmaceutical compositions comprising IGF-I/IGFBP-3 complexes. |
| 申请公布号 |
EP1828225(B1) |
申请公布日期 |
2010.03.03 |
| 申请号 |
EP20050854704 |
申请日期 |
2005.12.20 |
| 申请人 |
INSMED, INC. |
发明人 |
SLEEVI, MARK, C.;KELLEY, GLEN, L. |
| 分类号 |
C07K1/113;A61K38/30;C07K1/18;C07K14/47;C07K14/65 |
主分类号 |
C07K1/113 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
