SOLID PREPARATION COMPRISING 2- [ [6- [ (3R) -3-AMINO-1-PIPERIDIN YL] -3, 4-DIHYDR0-3-METHYL-2, 4-DI0X0-1 (2H) -PYRIMIDINYL] METHYL] -4-FLUOROBENZONITRILE.

摘要

The present invention provides a solid preparation containing 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dio xo-1(2H)-pyrimidinyl]methyl]-4-fluorobenzonitrile (compound (A)) or a salt thereof as a pharmaceutically active ingredient. Specifically, the present invention provides a solid preparation containing a granule composed of compound (A) or a salt thereof and an additive (excluding microcrystalline cellulose) and a tablet containing (a) a granule containing compound (A) or a salt thereof and microcrystalline cellulose, and (b) a tableting aid containing magnesium stearate and microcrystalline cellulose.