发明名称 |
NEW POLYMORPHISMS IN ABCB1 ASSOCIATED WITH A LACK OF CLINICAL RESPONSE TO MEDICAMENTS |
摘要 |
The present invention relates to methods, compositions, kits and reagents for determining the prognosis of a clinical response in a human patient to a medicament which acts in the central nervous system (CNS) and which is a substrate of the ABCB1 protein. Further, the invention relates to a combination of medicaments for the treatment of human patients having specific polymorphisms in the ABCB1 gene. |
申请公布号 |
EP2158331(A2) |
申请公布日期 |
2010.03.03 |
申请号 |
EP20080759217 |
申请日期 |
2008.06.12 |
申请人 |
MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. |
发明人 |
UHR, MANFRED;HOLSBOER, FLORIAN;MUELLER-MYHSOK, BERTRAM |
分类号 |
C12Q1/68;A61P25/24 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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