| 发明名称 |
METHODS AND COMPOSITIONS FOR INHIBITING IMMUNOGLOBULIN-MEDIATED-REPERFUSION INJURY |
| 摘要 |
<p>Methods and compositions for treating or preventing immunoglobulin-mediated reperfusion or ischemic injury, in a subject, are provided. Methods for identifying inhibitors of an interaction between a pathogenic immunoglobulin and an ischemic antigen or a component of the complement pathway are provided. Pathogenic immunoglobulins and mutated forms thereof are also disclosed.</p> |
| 申请公布号 |
EP1286682(B1) |
申请公布日期 |
2010.03.03 |
| 申请号 |
EP20010942082 |
申请日期 |
2001.06.08 |
| 申请人 |
IMMUNE DISEASE INSTITUTE, INC.;THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE;THE BRIGHAM AND WOMEN'S HOSPITAL, INC. |
发明人 |
CARROLL, MICHAEL C.;MOORE, FRANCIS D. JR.;HECHTMAN, HERBERT B. |
| 分类号 |
A61K38/00;G01N33/50;A61K38/02;A61K38/17;A61K39/395;A61K45/00;A61P9/10;C07H21/02;C07H21/04;C07K2/00;C07K14/00;C07K14/435;C07K16/00;C07K16/18;C07K16/28;C12N5/10;C12N15/09;C12P21/02;G01N33/15;G01N33/53;G01N33/58 |
主分类号 |
A61K38/00 |
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