发明名称 |
NUCLEIC ACIDS OF ROCHALIMAEA HENSELAE AND ROCHALIMAEA QUINTANA AND METHODS AND COMPOSITIONS FOR DIAGNOSING ROCHALIMAEA HENSELAE AND ROCHALIMAEA QUINTANA INFECTION |
摘要 |
A method of diagnosing cat scratch disease and a method of diagnosing bacill ary angiomatosis in a subject by detecting the presence of Rochalimaea henselae or an antigenic fragment thereof in the subject prov ided. Also provided is a vaccine comprising an immunogenic amount of a nonpathogenic Rochalimaea henselae or an immunogenically specifi c determinant thereof and a pharmaceutically acceptable carrier. A method of diagnosing Rochalimaea quintana infection in a subject by detecting the presence of a nucleic acid specific to Rochalimaea quintana in a sample from the subject is provided. A purified, 6 0-kDa heat shock protein of Rochalimaea is provided. Also provided is a 17-kDa antigenic polypeptide of Rochalimaea.
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申请公布号 |
CA2190359(C) |
申请公布日期 |
2010.03.02 |
申请号 |
CA19952190359 |
申请日期 |
1995.05.18 |
申请人 |
UNITED STATES GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE DEPARTME NT |
发明人 |
REGNERY, RUSSELL L.;ANDERSON, BURT E. |
分类号 |
C12N15/31;G01N33/569;A61K38/00;A61K39/00;A61K39/02;C07K14/195;C07K14/29;C12N15/09;C12P21/02;C12Q1/68;C12R1/19 |
主分类号 |
C12N15/31 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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