| 发明名称 |
PROCESS FOR THE SYNTHESIS OF E1 ACTIVATING ENZYME INHIBITORS. |
| 摘要 |
<p>The present invention provides processes and synthetic intermediates for the synthesis of 4-substituted ((1S, 2S, 4R)-2-hydroxy-4-{7H-pyrrolo[2/3-d]pyrimidin-7- yl}cyclopentyl)methyl sulfamates, which are El activating enzyme inhibitors, and are useful for the treatment of disorders of cell proliferation, particularly cancer, and other disorders associated with El activity.</p> |
| 申请公布号 |
MX2010001126(A) |
申请公布日期 |
2010.03.01 |
| 申请号 |
MX20100001126 |
申请日期 |
2008.08.01 |
| 申请人 |
MILLENNIUM PHARMACEUTICALS, INC. |
发明人 |
MARIANNE LANGSTON;STEVEN P. LANGSTON;HIROTAKE MIZUTANI;IAN ARMITAGE;ERIC L. ELLIOT;QUENTIN J. MCCUBBINU;MATTHEW STIRLING;LEI ZHU |
| 分类号 |
C07D487/04;C07C215/44;C07C217/52;C07C219/24 |
主分类号 |
C07D487/04 |
| 代理机构 |
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