发明名称 PHARMACEUTICAL COMPOSITION CONTAINING OPTICALLY ACTIVE COMPOUND HAVING THROMBOPOIETIN RECEPTOR AGONIST ACTIVITY AND INTERMEDIATE THEREOF.
摘要 <p>Disclosed is an optically active 4-phenylthiazole derivative having a thrombopoietin receptor agonist activity. Also disclosed is a pharmaceutical composition containing such a compound as an active ingredient, which makes an orally administrable platelet production control agent. Specifically disclosed is a pharmaceutical composition containing, as an active ingredient, an optically active compound represented by the formula below, a pharmaceutically acceptable salt thereof, or a solvate of any of them. (In the formula, R1 represents a halogen atom or a C1-C3 alkyloxy group; R2 represents a C1-C8 alkyl group; R3 represents a C1-C8 alkyl group; R4 and R5 independently represent a fluorine atom or a chlorine atom; R6 represents a C1-C3 alkyl group or a C1-C3 alkyloxy group; and * represents an asymmetric carbon atom.).</p>
申请公布号 MX2010001082(A) 申请公布日期 2010.03.01
申请号 MX20100001082 申请日期 2008.07.29
申请人 SHIONOGI & CO., LTD. 发明人 MASAMI TAKAYAMA;NORIYUKI KUROSE
分类号 C07D277/20;A61K31/426;A61P1/18;A61P7/00;A61P7/06;A61P43/00;C07D277/46 主分类号 C07D277/20
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