| 发明名称 |
Fremgangsmåde til direkte bestemmelse af individuelle methotrexatmeta-bolitter |
| 摘要 |
The present invention provides a method for determining a level of a methotrexate polyglutamate (MTXPG) in a cellular extract by resolving at least one MTXPG in a cellular extract obtained from a human undergoing methotrexate therapy; and detecting at least one resolved MTXPG, thereby determining a level of the resolved MTXPG. A method of the invention can be useful, for example, for determining a level of MTXPG 3 , MTXPG 4 or MTXPG 5 or for determining a level of each methotrexate polyglutamate species (MTXPG 1 to MTXPG 7 ) present in the cellular extract. |
| 申请公布号 |
DK1604203(T3) |
申请公布日期 |
2010.03.01 |
| 申请号 |
DK20040716493T |
申请日期 |
2004.03.02 |
| 申请人 |
PROMETHEUS LABORATORIES, INC. |
发明人 |
RICHERSON, RUSSELL;DERVIEUX, THIERRY |
| 分类号 |
G01N33/48;A01N1/02;C12Q1/00;C12Q1/02;G01N;G01N21/62;G01N21/75;G01N30/02;G01N33/00;G01N33/94 |
主分类号 |
G01N33/48 |
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