Particles having hydrophobic material therein

摘要

Disclosed is a process for preparing particles having a hydrophobic material therein, said process comprising: providing a multiple emulsion comprising a first emulsion dispersed in a hydrophobic medium, said first emulsion comprising a hydrophobic phase dispersed in a hydrophilic phase, wherein the hydrophobic phase comprises the hydrophobic material and the hydrophilic phase comprises a precursor which is capable of reacting to form a non-fluid matrix; and reacting the precursor in the multiple emulsion to form the matrix in the form of the particles having the hydrophobic material therein; wherein the precursor is added prior to formation of the multiple emulsion. Also disclosed is a use of a particle for the manufacture of a medicament for the treatment of a condition selected from the group consisting of cancer, diabetes, AIDS, hormonal dysfunction, hypertension and pain.