Provided is the use of an antibody or fragment thereof or a nucleic acid encoding said antibody or fragment thereof in the preparation of a medicament for the treatment of an angiogenesis-mediated disorder or condition wherein the antibody or fragment thereof binds cathepsin S and inhibits its proteolytic activity. Further provided is an antibody with specified sequence that binds cathepsin S and inhibits its proteolytic activity as well as corresponding nucleic acids and methods of producing such antibodies.
申请公布号
NZ563273(A)
申请公布日期
2010.02.26
申请号
NZ20060563273
申请日期
2006.04.10
申请人
FUSION ANTIBODIES LTD
发明人
SCOTT, CHRISTOPHER;BURDEN, ROBERTA;OLWILL, SHANE;WALKER, BRIAN;JOHNSTON, JIM