发明名称 |
TREATMENT FOR DARK ADAPTATION |
摘要 |
The present invention addresses the treatment of age-related macular degeneration using regulation of pathogenic mechanisms similar to atherosclerosis. In further specific embodiments, compositions that increase reverse cholesterol transport are utilized as therapeutic targets for age-related macular degeneration. In a specific embodiment, the lipid content of the retinal pigment epithelium, and/or Bruch's membrane is reduced by delivering Apolipoprotein A1, particularly a mimetic peptide.
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申请公布号 |
US2010047330(A1) |
申请公布日期 |
2010.02.25 |
申请号 |
US20080245944 |
申请日期 |
2008.10.06 |
申请人 |
SCHWARTZ DANIEL M;DUNCAN KEITH G;BAILEY KATHY R;KANE JOHN P;ISHIDA BRIAN Y |
发明人 |
SCHWARTZ DANIEL M.;DUNCAN KEITH G.;BAILEY KATHY R.;KANE JOHN P.;ISHIDA BRIAN Y. |
分类号 |
A61K9/127;A61K31/56;A61K31/66;A61K38/17;A61P27/02 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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