发明名称 |
COMPOSITIONS AND METHODS FOR INHIBITING NADPH OXIDASE EXPRESSION |
摘要 |
One or more inhibitors, in particular siRNAs, which down-regulate the expression of a NOX gene selected from the group consisting of NOX4, NOXI, NOX2 (gp91phox, CYBB), NOX5, DUOX2, NOXOI, NOXAI and NOXA2 (p67phox) is disclosed Also provided is a vector capable of expressing the compound A method is provided for treating or preventing the incidence or seventy of various diseases or conditions associated with NOX gene comppsing administering to the patient the inhibitor in a pharmaceutical composition |
申请公布号 |
WO2008152636(A3) |
申请公布日期 |
2010.02.25 |
申请号 |
WO2008IL00797 |
申请日期 |
2008.06.12 |
申请人 |
QUARK PHARMACEUTICALS, INC.;KALINSKI, HAGAR;METT, IGOR;FEINSTEIN, ELENA |
发明人 |
KALINSKI, HAGAR;METT, IGOR;FEINSTEIN, ELENA |
分类号 |
C07H21/00 |
主分类号 |
C07H21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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