METHODS FOR USING HUMAN NEUTROPHIL ELASTASE AS AN INDICATOR OF ACTIVE WOUND INFECTION

摘要

Measuring the level of HNE activity in the wound site enables diagnosing whether a chronic wound has active infection A FRET peptide substrate containing an HNE-specific amino acid sequence is incubated with wound fluid and measured for fluorescent radiation to determine the level of HNE activity The HNE diagnostic test is a rapid, point-of-care indicator of the level of HNE activity in wound fluid as an indicator of "active" infection.