| 摘要 |
<p>The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.</p> |
| 申请人 |
NOVARTIS AG;ASTEX THERAPEUTICS LTD. |
发明人 |
BESONG, GILBERT;BRAIN, CHRISTOPHER THOMAS;BROOKS, CLINTON A.;CONGREVE, MILES STUART;DAGOSTIN, CLAUDIO;HE, GUO;HOU, YING;HOWARD, STEVEN;LI, YUE;LU, YIPIN;MORTENSON, PAUL;SMITH, TROY;SUNG, MOO JE;WOODHEAD, STEVEN;WRONA, WOJCIECH |
