| 发明名称 |
QUINAZOLINES FOR PDK1 INHIBITION |
| 摘要 |
The invention provides quinazoline compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.
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| 申请公布号 |
US2010048561(A1) |
申请公布日期 |
2010.02.25 |
| 申请号 |
US20070295967 |
申请日期 |
2007.04.05 |
| 申请人 |
NOVARTIS VACCINES & DIAGNOSTICS, INC. |
发明人 |
RAMURTHY SAVITHRI;LIN XIAODONG;SUBRAMANIAN SHARADHA;RICO ALICE C.;WANG XIAOJING M.;JAIN RAMA;MURRAY JEREMY M.;BASHAM STEVEN E.;WARNE ROBERT L.;SHU WEI;ZHOU YASHEEN;DOVE JEFFREY;AIKAWA MINA;AMIRI PAYMAN;WANG WEIBO;JANSEN JOHANNA M.;WAGMAN ALLAN S.;PFISTER KEITH B.;NG SIMON |
| 分类号 |
A61K31/517;A61K31/5377;A61P35/00;C07D239/84;C07D401/12;C07D401/14;C07D413/14 |
主分类号 |
A61K31/517 |
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